Aloe leaf extract has been used for thousands of years to promote the health of epithelial tissue, including the bowel lining. Aloe is one of a class of compounds called anthraquinone glycosides. When ingested, these molecules are activated through bacterial metabolism in the gut. They promote water retention in the stool and stimulate peristalsis in the large intestine. By stimulating active chloride secretion, aloe increases the water and electrolyte content in the stool[1-4] and eases its passage without the artificial additives and associated cramping common to other therapies.